Is Real World Evidence Helpful in Clinical Trials?

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Real World Evidence is the clinical evidence that a particular medicine or product is developed after analyzing Real World Data (RWD). RWD is the data relating to healthcare delivery or patient status, which can be derived from clinical trials summits.

Real World Evidence, or RWE, is fundamentally changing the future of healthcare. We all know that analytics and in-depth studies result in data conversion to RWE. The RWE provides clinically rich insights into daily practices. Here, we will discuss whether RWE is helpful in clinical trials.

What is Real World Evidence?

Real World Evidence is the clinical evidence that a particular medicine or product is developed after analyzing Real World Data (RWD). RWD is the data relating to healthcare delivery or patient status, which can be derived from clinical trials events.

The sequence of events is that the data collected by pharmaceutical event management companies is analyzed, and RWE is found in various ways and can result from data collected from a large population.

Why Do We Need Real World Evidence?

Research is done in labs, and the results may differ from how patients react to various medicines in real life. RWD is based on patients recording their health issues, symptoms, treatments and medication reactions. Every clinical trials summit provides real data about people who matter the most in any medical discovery.

Drug development, treatments, and learning about illnesses can all be more impactful if RWE is compiled. RWE provides a holistic view of the patient’s experiences and the best drugs for any treatment based on factual data instead of curated and collected in traditional medical trials. 

RWE is an integral part of any drug discovery or clinical trials summits because it can reflect the real data collected from individuals from a diverse sample group. Therefore, the results can be more reliable. 

Moreover, RWE can be an excellent supplement to clinical trials, which may depict the results for a controlled group, while RWE can be based on a vast population. 

How is Real World Evidence Used?

RWE is used in the healthcare system in numerous ways. In life science research, physicians’ office data regarding patient history and treatments, and even for policy-making, RWE is used everywhere. 

Life science research

Biopharmaceutical companies and life science researchers use RWE as it can complement the findings of clinical trials completed in traditional ways. If a medicine is under research, RWE can help conclude the medicine’s use. The safety and impact of new treatments can also be done more accurately with RWE. 


RWE can help policymakers decide if a particular drug is safe when any new policy for public health concerns is underway. Moreover, they can understand the adverse effects of each medicine more accurately. RWE can help them decide if any medicine should be introduced or if any medicine used should be discontinued. 

Healthcare providers

RWE can provide insight into how a particular monitoring method, drug or medical condition can impact individuals. Healthcare providers can improve their service and use the most impactful medical equipment and medicines to improve healthcare for all. 

RWE is generated by RWD, which comes from a variety of sources. Health records, claims at pharmaceutical companies about any medicine’s results, disease registries, and data gathered from intelligent equipment like mobile apps and wearables can be used to collect data. 

Will Real World Evidence Replace Clinical Trials?

Medical communities rely on clinical trials summits and complete studies regarding drugs, various diseases and interventions in a controlled setting.

While some people may consider these trials as traditional and old-fashioned, they are not so traditional because of the latest technology. These trials have been the only method of discovering more about any new drug or health condition.

Clinical trials recruit participants and then study their health after drug administration or how each participant reacts to medicine.

These clinical trials have been the primary source of information for researchers. Pharmaceutical event management companies conduct clinical trials for drug discoveries or health monitoring.

Many people ask if RWE can replace clinical trials, and the answer is that RWE will not replace clinical trials because they are both needed to infer the effects of any drug or medical equipment. Moreover, a study was completed to see if RWE could replace clinical trials.

Around 220 clinical trials were observed and RWE replication was attempted. The result was that only 15% of the clinical trials could be replicated. This low replication rate showed that it will be long before we can say that clinical trials summits are redundant.


RWD is real-world data collected through various sources and displays the results of medicine use or any other pharmaceutical product on individuals. RWE is derived through this data and is a practical, helpful way to understand the impact of various medicines.

There are several uses of RWE, and it can be collected in various ways. However, in future, we do not see RWE replacing clinical trials as they are an integral part of any pharmaceutical event, which results in effective medication discovery.